All your FAQs answered for the use of Arthramid ® Vet in horses.
Have you seen any adverse reactions following the intra-articular injection of Arthramid ® Vet?
We have not seen any abnormal reaction in the joints in the research population. However, we allow the veterinarians involved in the field trial to use antibiotics simultaneously with Arthramid ® Vet. There are a few reported cases of granulomatous reactions when PAAG has been used concurrently with corticosteroids. Horses in this study must have no other treatments within 4 weeks of administration.
Does the articular treatment need to be repeated at a specific interval or 1 dose is enough?
One dose is often enough but this is something we are wanting to find out. Anecdotally repeating the dose either at 4 weeks for partial responders or at 6 months has been beneficial.
If horse does not improve, what is the course of action?
We recommend trying to understand why it didn’t work (further imaging, synovial fluid, other factors ( e.g. foot imbalance, conformation, work surface)...etc...). This is different from horses that are partial responders. These horses should be re-examined at 4-6 weeks and another dose administered as there is strong evidence that the mechanical effect is dose dependent. This is another aim of this study.
Can horses have some NSAID or other anti OA medications concurrent with Arthramid ® Vet?
NO NSAID, corticosteroids or other anti-OA medication should be injected.
Do you need synovial fluid from the joints, and if so, in any specific tube?
The synovial fluid can be put into sterile EDTA tubes and frozen at -20 degrees for up to 6 months. If collected, please let us know as we can arrange testing at a later date.
Is it ok to inject several OA joints in the same horse?
In the field trial, several joints can be injected in the same horse.
Any trials on horses with no visible arthritis but blocking to joint with suspicion of sub-chondral bone damage and or stress fractures?
AV is indicated for horses with proper diagnosis of OA. If these horses show signs of sub-chondral damage, we think that we can also treat such cases with Arthramid ® Vet.
Is Arthramid ® Vet indicated for osseous cyst-like lesions?
Practitioners have reported good results on cases with osseous cyst-like lesions in the stifle and fetlock.
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